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Is bipolar disorder autosomal or sex linkedJ Psychiatr Res. Assessing the role of X-linked inheritance in bipolar-related major affective disorder. Data from a family study of bipolar affective illness in New York are reexamined from the vantage point of X-linked dominant inheritance and genetic heterogeneity. For comparison, published data from a similar study in Bethesda and from a literature summary are also re-analyzed. The New York data support the presence of a change in rates of affective illness over time secular trend , with a substantial increase in risk at early ages for individuals born after Hence, risk ratios by sex of proband male vs female are calculated for each type of relative, thereby controlling simultaneously for generation and sex of relative. The risk ratios for all three studies are in the direction predicted by X-linkage.You may be more likely to develop bipolar disorder if you have a family in risky behavior, such as gambling, drunk driving, or impulsive sex. Inheritance of Single-Gene Disorders and Fundamentals - Learn about from the MSD Bipolar Disorder in Children and Adolescents (Manic-Depressive Illness) Recessive traits carried on autosomal chromosomes can be expressed only when An X-linked (sex-linked) gene is one that is carried on an X chromosome. Data from a family study of bipolar affective illness in New York () are the vantage point of X-linked dominant inheritance and genetic heterogeneity. Hence, risk ratios by sex of proband (male vs female) are calculated for each...the end of the story look at the video above ↑ ↑ ↑

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