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These behaviors can be modified by various environmental and physiological cues, although the molecular and cellular mechanisms that mediate these effects remain poorly understood. Recently, it has become clear that both the juvenile and adult hypothalamus exhibit ongoing neurogenesis, which serve to modify homeostatic neural circuitry. In this report, we share new findings on the contributions of sex-specific and dietary factors to regulating neurogenesis in the hypothalamic mediobasal hypothalamus, a recently identified neurogenic niche. We report that high fat diet HFD selectively activates neurogenesis in the median eminence ME of young adult female but not male mice, and that focal irradiation of the ME in HFD-fed mice reduces weight gain in females but not males. These results suggest that some physiological effects of high fat diet are mediated by the stimulation of ME neurogenesis in a sexually dimorphic manner.This may correspond to biological sex or may not. Nouns which have biologically masculine or feminine referents will correspond in gender. Thus walad 'boy. Twelve intact and 12 docked Najdi lambs of equal numbers of males and females were utilized in the experiment. Upon attaining 40 kg fasted and shorn body. Cre line, Reporter, Sex, Proposed neural progenitor cell, Age of induction . Sex- specific differences in diet-induced hypothalamic neurogenesis .. free article] [ PubMed] [CrossRef]; Haan N., Goodman T., Najdi-Samiei A...the end of the story look at the video above ↑ ↑ ↑
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